Drug Standards
Selleck Chemical LLC Toremifene Citrate 25mg 89778-27-8 NSC 613680
Toremifene Citrate (NSC 613680) is an oral selective estrogen receptor modulator (SERM), used in the treatment of advanced breast cancer. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Medchemexpress LLC 25-desacetyl rifampicin | 16783-99-6 | MFCD08063717 | >95.0% | 780.90 | C41H56N4O11 | 5MG
25-Desacetyl rifampicin is the deacetylated metabolite of rifampicin provided as an isotope-labeled (deuterated) reference standard for research use. It is intended for analytical quantitation and ADME/pharmacokinetic studies as a tracer or internal standard. The compound has CAS 16783-99-6, molecular formula C41H56N4O11, and molecular weight 780.90 g/mol. Documentation including a data sheet and safety data sheet is available from the supplier.
- Deuterated isotope-labeled reference standard.
- Suitable for pharmacokinetic and metabolic studies.
- High purity (≥95%).
- Molecular formula C41H56N4O11; molecular weight 780.90 g/mol.
- Available in small research pack sizes (1 mg-50 mg).
- Data sheet and safety data sheet available.
Selleck Chemical LLC Tazarotene 10mg 118292-40-3 AGN190168
Tazarotene (AGN190168) is a retinoid prodrug of tazarotenic acid, which is a RAR agonist, used to treat psoriasis, acne, and sun damaged skin. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Medchemexpress LLC Favipiravir impurity 5 | 1257072-34-6 | 5g
Favipiravir impurity 5 is an impurity of Favipiravir (HY-14768)
Medchemexpress LLC Tyrosinase-related protein 2 (TRP-2) (181-188) | 187671-49-4 | 99.06% | 1088.25 | 10 MG
Tyrosinase-related Protein 2 (TRP-2) (181-188) is a tyrosinase-related protein 2 (TRP-2)-derived peptide, corresponding to residues 180-188. It is the major reactive epitope within TRP-2 recognized by anti-B16 CTLs. This peptide conforms to the MHC class I H2-Kb binding motif.
- Derived peptide corresponding to residues 180-188
- Major reactive epitope within TRP-2
- Recognized by anti-B16 CTLs
- Conforms to MHC class I H2-Kb binding motif
Medchemexpress LLC Diclofenac Sodium | 15307-79-6 | 1 ML
Diclofenac Sodium is a potent and nonselective anti-inflammatory agent that functions as a COX inhibitor. It demonstrates inhibitory activity against human COX-1 and COX-2, and against ovine COX-1 and COX-2.
- Potent and nonselective anti-inflammatory agent
- Functions as a COX inhibitor
- Inhibits human COX-1 and COX-2 with IC50 values of 4 nM and 1.3 nM, respectively, in CHO cells
- Inhibits ovine COX-1 and COX-2 with IC50 values of 5.1 μM and 0.84 μM
- Can induce apoptosis in neural stem cells through activation of the caspase cascade
Medchemexpress LLC Cabozantinib impurity 7 | 1247859-37-5 | MFCD16676122 | 1g
Cabozantinib impurity 7 is an impurity of Cabozantinib (HY-13016)
Cayman Chemical Mifepristone Neurochemicals
An antagonist of glucocorticoid, progesterone, and androgen receptors (Kis = 0.1, 0.64, and 0.65 nM, respectively); selective for these receptors over MR, ERα, and ERβ (Kis = 640, >200, and >750 nM, respectively); inhibits R5020-stimulated alkaline phosphatase activity as well as reporter transcription stimulated by either dexamethasone or R5020 in cell-based assays (IC50s = 7, 5.9, and 1.3 nM, respectively); inhibits R1881-stimulated reporter transcription in a concentration-dependent manner; inhibits growth of 4-OHT-resistant MCF-7 breast cancer cells in vitro at 10 µM; inhibits tumor growth in an SKOV3 ovarian cancer nude mouse xenograft model at 0.5 or 1 mg per day